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Slit Lamp Optical Coherence Tomography Study Of Anterior Segment Changes After Phacoemulsification And Foldable Intraocular Lens Implantation
Sep 20, 2017

Summarize and analyze the clinical characteristics of viral corneal endotheliitis after corneal transplantation,and providing clinic guidance for diagnosis and treatment.Methods Twenty-four clinical cases with comeal endermatitis after keratoplasty referred to our hospital from January 2008 to October 2012 were retrospectively analyzed.Corneal edema,and the changes of endothelial surface KP were recorded under slit lamp microscope.The morphology and quantity of endothelial cell,along with the changes of endothelial surface KP also were examined by the laser scanning confocal microscope.Results Slit lamp microscope examinations showed that the corneal edema of graft and/or planting bed,and appearing scattered and patchy KP under endothelial surface,moreover,KP evenly distributed in the affected graft and planting beds.Confocal images revealed that:cell edema,highly inflammatory cell infiltration,loss of defined hexagonal cell boundaries,enlarged nuclei; different sizes and shapes of high reflective and scattered KP,gathered into a mass or cords; the visible dark areas with blurry borders and cell structure.After 710 days treatment by antiviral therapy combined with glucocorticoids,the patients' condition was controlled,and vision were improved than before.After 3 months treatment,the loss of endothelial cell was (9.9±2.1)%.Conclusions It needs consider the possibility of corneal endotheliitis when appearing graft edema,the surface endothelial and the change of KP after corneal transplantation,and grasping the clinical features,which plays an important role in improving the diagnostic level in our clinical practicing work.

Investigate quantitative changes of the anterior segment configuration after clear corneal incision phacoemulsification and foldable intraocular lens (IOL) implantation with slit-lamp-adapted optical coherence tomography (SL-OCT). Methods In prospective consecutive case series, clear corneal incision phacoemulsification and foldable intraocular lens implantation were performed in 44 eyes of 40 patients. The changes of the anterior segment configuration were performed by SL-OCT before and 1 day, 1 week, 2 weeks and 1 month after surgery. SPSS 16.0 software was used to analyze statistical difference. Results For all patients, the central corneal thickness (CCT) and the incisional corneal thickness (ICT) increased significantly 1 day after surgery ( CCT increased 99. 59 μm, ICT increased 234. 57 μm;P = O. 490). At 1 month, the CCT almost had returned to baseline, but the ICT had been ticker about 19. 25 μm than baseline (P=0. 001) . The measurements of ACD, AODS00, AOD750, TISAS00, TISA750 also increased significantly 1 day after surgery. Although the ACD had no changes within 2 weeks( all P <0.05), it had been not stable. The changes of the width of the anterior chamber had been stable in the early period after surgery ( all P>0. 05). Conclusion The SL-OCT could impersonality and quantificationally evaluate the anterior segment changes induced by cataract surgery

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